Abstracts Division 2

43. Accelerated 23-hour ERAS care for colorectal surgery (CHASE)

Thaís T.T. Tweed, Misha A.T. Sier, Michael. Bakens, Johan Nel, Sigrid de Jong-Zeijlmaker, Imane Daher, Chelsea van Es, Daisy Hoofwijk, Elise Machiels, James van Bastelaar, Jan H.M.B. Stoot

Zuyderland Medical Centre, Dept. of Surgery.  Henri Dunantstraat 5, 6419 PC Heerlen, the Netherlands.

Introduction
Introduction of the Enhanced Recovery After Surgery (ERAS) program has improved postoperative outcomes. The aim of this study was to investigate the feasibility and safety of a 23-hour accelerated ERAS protocol for patients undergoing colorectal surgery.

Methods
This single-center, non-randomized, prospective study was carried out in one large teaching hospital in the Netherlands. Patients (≥ 18 years ≤ 80) undergoing elective laparoscopic surgical resection, were invited to participate in this study if they met the following criteria: BMI ≤ 35 kg/m2, WHO performance status 0, available ambulant care and available by phone. The 23-hour accelerated ERAS protocol consisted of a multidisciplinary and multifaceted protocol adjusting the preoperative, perioperative and postoperative care as previously reported by Levy et al. If patients met the discharge criteria, they were discharged within 23-hours after surgery.  Primary outcome was the rate of the successful and safe application of the 23-hour accelerated ERAS protocol.

Results
Sixty-seven patients were eligible for inclusion, of whom 44 patients were included. Three patients were excluded; two due to conversion to an open procedure and one because of incorrect anesthesia. The preliminary results have shown that
33 (80%) patients were discharged on postoperative day 1 of initial admission.
Seven (17%) patients were readmitted. Twelve patients (29%) had a complication, of which 2 (5%) patients required reoperation; one patient had an anastomotic leakage and one patient had a trocar hernia. All patients rated the program ≥ 7, 76% even ≥ 9.

Conclusion
This study was the first Dutch study assessing the feasibility and safety of a 23-hour accelerated protocol for colorectal surgery. The preliminary results of our data suggest that: accelerated recovery with the CHASE protocol is feasible for the majority of patients, few patients developed a major complication requiring reoperation and all patients have appraised the program positively.

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