Abstracts Division 2
35. Assessing malnutrition in an unselected cohort of IBD outpatients
Evelien M.B. Hendrix,1,2,*, Corinne E.G.M. Spooren,1,2,*, Devina Grommen,1 Ad A.M.
Masclee,1,2 Marieke J. Pierik,1,2 Daisy M.A.E. Jonkers1,2
1 Department of Internal Medicine, Division of Gastroenterology and Hepatology, Maastricht University Medical Centre+, Maastricht, The Netherlands
2 School for Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University Medical Centre+, Maastricht, The Netherlands
* Shared first author
Background and aims
Inflammatory bowel disease (IBD) is associated with malnutrition, which can
further affect disease course and quality of life. Therefore, guidelines
advocate screening of patients in clinical practice. However, the prevalence of
malnutrition varies widely, due to differences in populations included and
parameters used. The primary aim of the present study was to assess the
prevalence of malnutrition using single and a combined set of parameters.
Secondary aims were i) to evaluate the accuracy of screening recommendations
given in current IBD guidelines and ii) to explore which patients have an
increased risk of malnutrition.
Methods
Malnutrition was defined by the Global Leadership Initiative on Malnutrition (GLIM) criteria
and by single parameters for impaired body composition, muscle strength or
caloric intake. Independent risk factors (i.e. clinical and demographic
factors) for malnutrition were analyzed by multivariable logistic regression.
Results
Of 200 included patients (139 CD, 61 UC), 40 (20%) fulfilled the GLIM
criteria, and 94 (47.0%) had at least one parameter for malnutrition impaired.
The fat free mass index was most often affected. When applying screening
according to current IBD guidelines, only 32 patients were identified. Only
female sex was associated with malnutrition (OR 2.57, 95% CI 1.40-4.72).
Conclusion
In total, 40 patients fulfilled the GLIM criteria and almost half of the IBD
outpatients had malnutrition as defined by various single parameters and
irrespective of disease characteristics. Screening for malnutrition is
recommend for all IBD outpatients by multiple parameters, with special
attention for assessing fat free mass and reduced intake.
NUTRIM | School of Nutrition and Translational Research in Metabolism
NUTRIM aims to contribute to health maintenance and personalised medicine by unraveling lifestyle and disease-induced derangements in metabolism and by developing targeted nutritional, exercise and drug interventions. This is facilitated by a state of the art research infrastructure and close interaction between scientists, clinicians, master and PhD students.
www.maastrichtuniversity.nl/nutrim